Do you have a volcardiac heart relic?

Someone should be in a shield set.

But i'm guessing the biggest issue is skill settings. make sure titus's a3 is locked out all the time, you don;t want him ally-protecting, that'll just eat his shields. and you don;t want him doing his nuke on ram form unless you're absolutely certain true fear is in place.

Are your champs fast enough? You want both wix and donnie to go before chimera gets its first turn, and open with a3, both of them should have a2 as top priority after opening.

Looks like you also want to get a res buff in place before chimera's first turn too.

Speed definitely the biggest issue.  Need to get buffs up before the boss goes and strips everything.  Also Graazur is kind of a weak option for an extender in this team since his buffs are already covered.  Mikage would be better if youve got her.