It's possible, yes, but it really depends on whether you can find a way to handle the stun. There are a few ways to do that, but the easiest relies upon essentially having someone with either unkillable, block damage, or revive on death become the stun target. There are a fair number of champs with self-buffs for those. Common choices are Skullcrusher, Torturehelm, and Bushi.
Another option is to use someone with a big shield to absorb most of the damage on the stun, so that you can survive despite being relatively squishy. Champs like Valkyrie and Helicath are the common choices, but there are others that also can put big shields up.
The last option, which is the trickiest by far, is to get a 3rd champ like Warcaster on the team, because if might be able to run two 4:3 champs and arrange it so one of them is last on turn 1, and the other is last on turn 3, and Demytha is last on turn 2.