Definetly not Relickeeper, who is offering absolutely nothing usefull at CB. Maybe he actually deals damage if you have Wamaster on him, but any lvl 60 champ could do the same.
Hope could be good, because her shields offer some usefull defense to the team. The shield is based on her HP, so she doesn't perform well because she is only lvl 50. Make her lvl 60 and use euip with main stats that fit (hp-%).
You should use a champ with atk debuff, that reduces the damage of CB a lot and gives you some extra turns, one of the most usefull buffs/debuffs at all in CB. Replace Relickeeper with a champ that does that on the long run.
The only reason i have relic keeper in is because hes one of my hardest hitting and one of the first rares i got. Hes just holding someone elses place i just dont know who yet.
You could at least replace Relickeeper by Cupidus, who will put some HP burn in addition to serious damage.
Using High Khatun could make sense too, especially if you put her in the lead spot for her aura. Although not sure if that would be an upgrade over Hope - Skadi is right that you really need decrease attack and until you get it, you'll die sooner than you should, so maybe you can't afford to lose Hope at the moment.
I just pulled apothecary should i replace someone on my team with him?
If you just pulled hi: no. But when he reaches lvl 60 and has Giantslayer masterie skilled: yes, replace Relickeeper.
/edit: If you are talking about replacing somebody from the team Player J recommended: Replace Warmaiden. I don't know why she is in that team anyway, Fahrakin allready offers decrease def on his A1.