For demon lord you have an easy 1-key UNM team:

Wixwel, anchorite, lakanis, elva and any dps

thanks @MooredRat, I'd love to hear your thoughts on Team Hydra.

I am open to different suggestions.

Well, hydras a lot more complicated, and I think there are others here on the forums who can do a better job giving advice than I can.

But as a starting point:

Since you don't have Shamael, you'll almost certainly want Rector on the team so that veils can counter the fear head.

You'll want Uugo or Lazarius to place block buffs.

Bivald or Wixwell for provoke

Akemtum or Cleo to place hex.

Oboro is actually a really good hydra DPS, even moreso when you get Mikage to partner with.

Edit: but get a 2nd and 3rd opinion from someone smarter'n me before you go dumping resources into champs :)

thanks again. Your ideas will also be useful to me when forming different teams.

The biggest thing you need to understand about Hydra is the mechanics and how champs interact with them. Unlike CB, Hydra really isn't a "run it on auto", at least not until you understand what's going on. Essentially there are four main things you need to deal with for Hydra to work properly:

1) Head of Decay

This is the one that tends to ruin most peoples' runs. Decay does two really terrible things to you if he isn't controlled. He removes ALL debuffs from ALL heads, AND he gives them all a turn-meter boost. That is very often simply the end of the run, especially when combined with what the other heads can do. There's only one way to control him - Provoke. So, just about every Hydra team, except the really top-end ones that just oneshot him every time, basically require Provoke.

From your roster, you have a bunch of options, but what it comes down to, and I'll repeat this throughout, is - do you have books. Because Provoke champs NEED to be booked on their Provoke skill, both to reduce the cooldown and increase the chance of landing.

Wixwell & Bivald are both solid choices, as Rat mentioned, but Wixwell will probably not work on auto, since there's no guarantee he targets Decay with his A1. Wix can also work unbooked, since his A1 on bosses is 80% x2, which is close enough to a guarantee.

2) Head of Mischief

He's the annoying one, and he can definitely ruin runs too, though he doesn't tend to do it with the same "oomph" as Decay. You deal with him in one of three ways. Either you have enough resist on everyone to just resist his buff-steal, or you have enough resist on one or two champs AND you can guarantee they always have the bost buffs, or you use block debuffs to just prevent his buff-stealing from being too problematic. The last option is the worst of them, because even though he won't steal your buffs, he'll still remove them and steal your turn-meter, which means he's getting more turns, and that means you're getting eaten faster.

Unfortunately for now you probably don't have the luxury of choice, so, as mentioned by Rat, just go with Uugo to place the block buffs, assuming you haven't got Lazarius booked on his A2.

3) Head of Torment

Definitely annoying, but he's less so because you can avoid attacking him for the most part. Still, it definitely helps to run Veil or Perfect Veil instead. If he's booked Loki can probably do the job best, if not, Drath is a solid choice.

4) Head of Blight

You need to deal with the poison cloud, or else everything else falls apart pretty fast. Fortunately you have Uugo for that already, so you're set.

So, with all that in mind, your team so far is looking like:

1) Wixwell

2) Uugo

3) Drath

That leaves room for three more people. You definitely need damage, and on the lower difficulties, that's best-done by just using direct face damage. Pick your best-geared champs. Ninja and Artak are very good choices. So is Rathalos, if you've got him booked. There's lots to choose from, but you probably want to pick your best two.

For the last slot, you'll want utility. Things that are very useful to bring are Speed Up, Speed Down, Acc Up, and Acc Down, so try to pick someone who can do multiple of those.

hi @kramaswamy.kr, thank you very much for the hydra handbook. It will be very helpful for beginners. I have the books, I don't use them until I have my champions completely stacked. I was not aware of the powers of my champions until I understood hydra. Thank you very much.

Your roster is pretty impressive given its size, you'll have 4 Mythicals once you fuse Mikage. You have a ton of options for Hydra, I guess the question is what difficulty are you going for? Normal/Hard you might be able to do 100mil damage easily (depending on gear). 

I don't have Wixwell but I know he's still viable. Uugo is one of the best Hydra debuffers because of how their mechanics work AND they have a cleanse that also always removes Heal Reduction. That being said, you have Lazarius who has an amazing kit for stripping enemy buffs, doing block buffs on them, doing block debuffs on your team AND increase atk AND strengthen. 

Wixwell might synergize with Lazarius and Wixwell's A1 can lock down Decay head with provoke. 

For Hex, Artak in Hex is solid till you get Mithrala from Hydra chests. 

Lazarius's A2 might ignore Poison Cloud since the Buff Reduction and Block Buffs aren't directly paired with the damage. 

You've been given some great feedback so far, the last thing I will say about Hydra is you want to make a squad that does the following:

Team Inc Atk, Spd, Def

Enemy Dec Def, Atk, Spd, Weaken, Block Buffs, Hex and Provoke

The problem is I'm not sure you have anyone on your Roster other than Elva and Apothecary that does Inc Speed. Elva would be the only one worth bringing to Hydra but then you're doubling up on a lot of buffs. Also other than Uugo, I'm not seeing a great AOE Decrease Defense (but I don't know all your champions).

How close are you to getting Lydia? Lydia would round out your team really well. 

My best suggestion based on who you currently have for a Semi/Full Auto Team would be: Artak (cursed set), Wixwell, Lazarius, Uugo, Rathalos and Ninja. Also make sure Lazarius stays in base form. At the start of the fight, if Decay and Poison heads are present, make sure Wixwell does his A1 first on Decay for Provoke and then get Block Buffs out immediately so no Poison Cloud on any heads.

TECHNICALLY since Rathalos and Ninja both do Dec Defense on their A1, if you're manual-only you might be able to skip using Uugo. Once you get Lydia, swap Lydia in for Uugo. 

Lastly, if you're running full Auto, don't worry about Veil/Perfect Veil for the team since you can just re-run the fight if RNG screws you up.

IF you get lucky and pull Shamael from a void shard DO NOT BRING VEIL! You want as many fears to be attempted as possible to max Shamael's passive TM Fill.

I had another thought and since my previous post was too long, I'll just set it here:

Putting Uugo and Lazarius in Cursed Sets you could do:

Lazarius, Uugo, Elva, Wixwell, Ninja and another DPS (possibly Rathalos). That wouldn't be a super high damage team but you would have a LOT of survivability and you've got stacking cleanses to the point that Fear Head wouldn't even be a concern at that point so no Veils needed other than the ones already present in some of the above champions

hi @Onikage55, I think like you, I have a lot of skills as a champion, but they are not compatible with each other. That's why it's hard to form a team. I think it would be more logical to act according to the hex relic. I will act accordingly when forming the team. You approached from a very different angle, I had never thought of playing with relics. I am very far from Lydia, so I can't count her. Artak (cursed set), Wixwell, Lazarius, Uugo, Rathalos and Ninja sets and @kramaswamy.kr's set are very similar, I will completely line up Lazarius and Drath and try both. 

Thank you very much for your opinions.

Lastly, do you have any recommendations for a Rathalos kit?

Rathalos honestly is a No Acc champion for bosses. Especially with aoe hp burners for his bonuses.

Some even turn his A3 off on presets so that his A2 has (theoretically) more chances to do the AOE + 4x from passive. If you are doing manual, you can use his A3. He also works well in a Bloodshield accessory, especially with his A2 doing AOE every other hit. Get his 100% Crit Rate and balance Atk/Spd/Crit Dmg as best you can