I've noticed that when I play Dungeons or CB with my Royal Guard on Auto, the Takedown attack will not always trigger.

Against the Spider it tends to take 6 or 7 turns to trigger, while obviously it should be triggered in turn 1 or 2.

Against the Clan Boss it often doesn't trigger at all. I've checked several times now switching auto off, checking the attack is available, turning auto back on only to see RG just use his default attack.

As Takedown is the main reason to use this hero, it renders him pretty useless unless you play manually, which isn't an option as the game already takes me 2 hours per day to stay on top of without trying manual combat.